2016

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Year: 2016

Authors: Suzuki K., Tsunekawa Y., Hernandez-Benitez R., Wu J., (...) Magistretti P., Callaway E.M., Zhang K., Belmonte J.C.

Mammalia
Rattus
Genome
Homology
Engineered nucleases
Biomedical Research

A motion capture study to measure the feeling of synchrony in romantic couples and in professional musicians

Year: 2016 ISSN:DOI: 10.3389/fpsyg.2016.01673

Authors: Preissmann D., Charbonnier C., Chagué S., Antonietti J.P., Llobera J., Ansermet F., Magistretti P.J.

Mirror game
Motion capture
Musicians
Quality of interactions
Subjective feeling
Synchrony

Astrocyte β2-=adrenergic receptors mediate hippocampal long-term memory consolidation

Year: 2016 ISSN:DOI: 10.1073/pnas.1605063113

Authors: Gao V., Suzuki A., Magistretti P.J., Lengacher S., Pollonini G., Steinman M.Q., Alberini C.M.

Astrocyte
Hippocampus
Lactate
Memory
β- Adrenergic receptor

Glutamate cysteine ligase-modulatory subunit knockout mouse shows normal insulin sensitivity but reduced liver glycogen storage

Year: 2016 ISSN:DOI: 10.3389/fphys.2016.00142

Authors: Lavoie S., Steullet P., Kulak A., Preitner F., Do K.Q., Magistretti P.J.

Cortisol
GCLM knockout
Glutathione
Glycemia
Glycogen
Insulin
Resident-intruder stress

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Year: 2016 ISSN:DOI: 10.1111/jsr.12419

Authors: Baud M.O., Parafita J., Nguyen A., Magistretti P.J., Petit J.M.

Strocyte–neurone lactate shuttle
Beta rhythm
Energy metabolism
Exploratory behavior
Neurometabolic coupling

The HDAC inhibitor SAHA improves depressive- like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Year: 2016 ISSN:DOI: 10.1016/j.neuropharm.2016.03.012

Authors: Meylan E.M., Halfon O., Magistretti P.J., Cardinaux J.R.

Animal model of depression
Antidepressants
BDNF
CREB coactivator
Epigenetics
HDAC inhibitor
Mood disorders

The subjective sensation of synchrony: an experimental study

Year: 2016 ISSN:DOI: 10.1371/journal.pone.0147008

Authors: Llobera J., Charbonnier C., Chagué S., Preissmann D., Antonietti J.P., Ansermet F., Magistretti P.J.

Synchrony
People behavior
Behavioral mechanisms

In vivo evidence for a lactate gradient from astrocytes to neurons

Year: 2016 ISSN:DOI: 10.1016/j.cmet.2015.10.010

Authors: Mächler P., Wyss M.T., Elsayed M., Stobart J., Gutierrez R., Von Faber-Castell A., Kaelin V., Zuend M., San Martín A., Romero-Gómez I., Baeza-Lehnert F., Lengacher S., Schneider B.L., Aebischer P., Magistretti P.J., Barros L.F., Weber B.