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Laboratory of Cellular Imaging and Energetics
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2012

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Simultaneous optical recording in multiple cells by digital holographic microscopy of chloride current associated to activation of the ligand-gated chloride channel GABA(A) receptor
Year: 2012 ISSN:DOI: 10.1371/journal.pone.0051041
Authors: Jourdain P., Boss D., Rappaz B., Moratal C., Hernandez M.C., Depeursinge C., Magistretti P.J., Marquet P.
  • Chloride Channels
  • Chlorides
  • Gamma-Aminobutyric Acid
  • HEK293 Cells
  • Holography
  • Humans
  • Ion Channel Gating
  • Membrane Potentials
  • Microscopy
  • Receptors
New evidence of neuroprotection by lactate after transient focal cerebral ischaemia: extended benefit after intracerebroventricular injection and efficacy of intravenous administration
Year: 2012 ISSN:DOI: 10.1159/000343657
Authors: Berthet C., Castillo X., Magistretti P.J., Hirt L..
  • Cerebral ischaemia
  • Lactate
  • Middle cerebral artery occlusion
  • Neuroprotection
  • Stroke
  • Translational research
Label-free cytotoxicity screening assay by digital holographic microscopy
Year: 2012 ISSN:DOI: 10.1089/adt.2012.476
Authors: Kühn J., Shaffer E., Mena J., Breton B., Parent J., Rappaz B., Chambon M., Emery Y., Magistretti P., Depeursinge C., Marquet P., Turcatti G.
  • Biological Assay
  • Drug Evaluation
  • Preclinical
  • Equipment Design
  • Equipment Failure Analysis
  • Holography
  • Image Interpretation
Spatially-resolved eigenmode decomposition of red blood cells membrane fluctuations questions the role of ATP in flickering
Year: 2012 ISSN:DOI: 10.1371/journal.pone.0040667
Authors: Boss D., Hoffmann A., Rappaz B., Depeursinge C., Magistretti P.J., Van De Ville D., Marquet P.
  • Adenosine triphosphate
  • Algorithms
  • Erythrocyte deformability
  • Erythrocyte membrane
  • Erythrocytes
  • Humans
​Sustained sleep fragmentation affects brain temperature, food intake and glucose tolerance in mice
Year: 2012 ISSN:DOI: 10.1111/j.1365-2869.2012.01029.x
Authors: Baud M.O., Magistretti P.J., Petit J.M.
  • Glucocorticoids
  • Locomotor activity
  • Metabolism
  • Obstructive sleep apnea
Oligodendroglia metabolically support axons and contribute to neurodegeneration
Year: 2012 ISSN:DOI: 10.1038/nature11314
Authors: Morrison B.M., Lee Y., Li Y., Lengacher S., Farah M.H., Liu Y., Tsingalia A., Jin L., Zhang P.W., Griffin J.W., Pellerin L., Magistretti P.J., Rothstein J.D.
  • Biochemistry
  • Brain
  • Cytology
  • Epidemiology
  • Functional role
  • Glucose
  • Metabolite
  • Nervous system disorder
  • Neurology
  • Rodent
  • Survival
  • Tumor
Deletion of CREB-regulated transcription coactivator 1 induces pathological aggression, depression-related behaviors, and neuroplasticity genes dysregulation in mice
Year: 2012 ISSN:DOI: 10.1016/j.biopsych.2012.04.011
Authors: Breuillaud L., Rossetti C., Meylan E.M., Mérinat C., Halfon O., Magistretti P.J., Cardinaux J.R.
  • Antidepressant
  • BDNF
  • CREB
  • Fluoxetine
  • Major depression
  • Mood disorders
  • Neuroplasticity genes regulation
  • Transcriptional coactivator
Brain lactate metabolism in humans with subarachnoid haemorrhage
Year: 2012 ISSN:DOI: 10.1161/STROKEAHA.111.648568
Authors: Oddo M., Levine J.M., Frangos S., Maloney-Wilensky E., Carrera E., Daniel R.T., Levivier M., Magistretti P.J., LeRoux P.D.
  • Brain hypoxia
  • Cerebral metabolism
  • Hyperglycolysis
  • Lactate
  • Subarachnoid hemorrhage
Early cell death detection with digital holographic microscopy
Year: 2012 ISSN:DOI: 10.1371/journal.pone.0030912
Authors: Pavillon N., Kühn J., Moratal C., Jourdain P., Depeursinge C., Magistretti P.J., Marquet P.
  • Brain cell
  • Cell death
  • Cell viability
  • Cell volume
  • Controlled study
  • Digital holographic microscopy
  • Early diagnosis
  • Microscopy
  • Mouse
  • Nonhuman
  • Quantitative analysis
  • Signal detection
Sweet sixteen for ANLS
Year: 2012 ISSN:DOI: 10.1038/jcbfm.2011.149
Authors: Pellerin L., Magistretti P.J.
  • Astrocytes
  • Brain imaging
  • Energy metabolism
  • Lactate
  • Neurodegeneration
  • Neuronal-glial interaction
Memory reconsolidation: trace reassociation and the freudian unconscious
Year: 2012 ISSN:DOI: 10.1016/B978-0-12-386892-3.00014-7
Authors: Alberini C.M., Ansermet F., Magistretti P.
  • Consolidation
  • Freud
  • Memory
  • Psychoanalyss
  • Reconsolidation
  • Retrieval
  • Unconscious
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