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Laboratory of Cellular Imaging and Energetics
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2015

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Improvement of neuroenergetics by hypertonic lactate therapy in patients with traumatic brain injury is dependent on baseline cerebral lactate/pyruvate ratio
Year: 2015 ISSN:DOI: 10.1089/neu.2015.4057
Authors: Quintard H., Patet C., Zerlauth J.B., Suys T., Bouzat P., Pellerin L., Meuli R., Magistretti P.J., Oddo M.
  • Cerebral blood flow
  • Cerebral microdialysis
  • Hypertonic
  • Lactate
  • Traumatic brain injury
​Learning-induced gene expression in thehippocampus reveals a role of neuron – astrocyte metabolic coupling in long term memory
Year: 2015 ISSN:DOI: 10.1371/journal.pone.0141568
Authors: Tadi M., Allaman I., Lengacher S., Grenningloh G., Magistretti P.J.
  • Avoidance behavior
  • Brain Mapping
  • Controlled study
  • Energy metabolism
  • Gene
  • Gene Expression
  • Glut1 gene
Disrupting astrocyte-neuron lactate transfer persistently reduces conditioned responses to cocaine
Year: 2015 ISSN:DOI: 10.1038/mp.2015.157
Authors: Boury-Jamot B., Carrard A., Martin J.L., Halfon O., Magistretti P.J., Boutrel B.
  • Astrocyte-neuron lactate
  • Drug addiction
  • Glycogen-derived lactate transfer
Influence of MCHR2 and MCHR2-AS1 genetic polymorphisms on body mass index in psychiatric patients and in population-based subjects with present or past atypical depression
Year: 2015 ISSN:DOI: 10.1371/journal.pone.0139155
Authors: Delacrétaz A., Preisig M., Vandenberghe F., Saigi Morgui N., Quteineh L., Choong E., Gholam-Rezaee M., Kutalik Z., Magistretti P., Aubry J.M., Von Gunten A., Castelao E., Vollenweider P., Waeber G., Conus P., Eap C.B.
  • Atypical depression
  • Body mass
  • Controlled study
  • Gene replication
  • Genetic association
  • Haplotype
  • Heterozygosity
Association of PCK1 with body mass index and other metabolic features in patients with psychotropic treatments
Year: 2015 ISSN:DOI: 10.1097/JCP.0000000000000388
Authors: Saigi Morgui N., Vandenberghe F., Delacrétaz A., Quteineh L., Choong E., Gholamrezaee M., Magistretti P., Aubry J.M., Von Gunten A., Preisig M., Castelao E., Vollenweider P., Waeber G., Kutalik Z., Conus P., Eap C.B.
  • Body Mass Index
  • Metabolic syndrome
  • Pharmacogenetics
  • Psychotropic drugs
​Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2
Year: 2015 ISSN:DOI: 10.1016/j.cellsig.2015.08.001
Authors: Kovács K.A., Steinmann M., Halfon O., Magistretti P.J., Cardinaux J.R.
  • CBP
  • Coactivator
  • HIPK2
  • Protein kinase
  • Transcriptional regulation
Embodied memory: unconscious smiling modulates emotional evaluation of episodic memories
Year: 2015 ISSN:Doi: 10.3389/fpsyg.2015.00650
Authors: Arminjon M., Preissmann D., Chmetz F., Duraku A., Ansermet F., Magistretti P.J.
  • Embodied cognition
  • Facial feedback hypothesis
  • Memory
  • Reconsolidation
  • Somatic markers
Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling
Year: 2015 ISSN:DOI: 10.1016/j.bbi.2015.04.013
Authors: Eis T., Allaman I., Gentner M., Schroder K., Tschopp J., Magistretti P.J., Schaeren-Wiemers N.
  • Astrocyte-neuron lactate shuttle
  • Brain energy homeostasis
  • Cerebral cortex
  • Gray matter pathology
  • Inflammasomes
  • Multiple Sclerosis
  • Normal appearing gray matter
Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa
Year: 2015 ISSN:DOI: 10.1038/mp.2015.26
Authors: Shih P.B., Yang J., Morisseau C., German J.B., Zeeland A.A., Armando A.M., Quehenberger O., Bergen A.W., Magistretti P., Berrettini W., Halmi K.A., Schork N., Hammock B.D., Kaye W.
  • Adolescent
  • Adult
  • Anorexia nervosa
  • Anxiety
  • Biological functions
  • Body mass
  • Controlled study
  • Enzyme activity
Neuroenergetic response to prolonged cerebral glucose depletion after severe brain injury and the role of lactate
Year: 2015 ISSN:DOI: 10.1089/neu.2014.3781
Authors: Patet C., Quintard H., Suys T., Bloch J., Daniel R., Pellerin L., Magistretti P., Oddo M.
  • Brain injury
  • Cerebral metabolism
  • Cerebral microdialysis
  • Glucose
  • Lactate
Channel-mediated lactate release by K⁺-stimulated astrocytes
Year: 2015 ISSN:DOI: 10.1523/JNEUROSCI.5036-14.2015
Authors: Sotelo-Hitschfeld T., Niemeyer M.I., Mächler P., (....) San Martín A., Le Douce J., Bonvento G., Magistretti P.J., Sepúlveda F.V., Weber B., Barros L.F.
  • Fluorescence microscopy
  • Genetically encoded nanosensor
  • Gliotransmission
  • Membrane depolarization
Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments
Year: 2015 ISSN:DOI: 10.1097/FPC.0000000000000131
Authors: Quteineh L., Vandenberghe F., Saigi Morgui N., Delacrétaz A., Choong E., Gholam-Rezaee M., Magistretti P., Bondolfi G., Von Gunten A., Preisig M., Castelao E., Vollenweider P., Waeber G., Bochud M., Kutalik Z., Conus P., Eap C.B.
  • Body Mass Index
  • Metabolic syndrome
  • Pharmacogenetics
  • Psychotropic drugs
Multi-timescale modeling of activity-dependent metabolic coupling in the neuron-glia-vasculature ensemble
Year: 2015 ISSN:DOI: 10.1371/journal.pcbi.1004036
Authors: Jolivet R., Coggan J.S., Allaman I., Magistretti P.J.
  • Computational Biology
  • Computer Simulation
  • Extracellular Space
  • Glucose
  • Humans
  • Lactic Acid
  • Models
  • Cardiovascular
A new outlook on mental illnesses: glial involvement beyond the glue
Year: 2015 ISSN:DOI: 10.3389/fncel.2015.00468
Authors: Elsayed M., Magistretti P.J.
  • Astrocyte
  • Cognition
  • Glia
  • Microglia
  • Mood
  • NG2 glia
  • Oligodendrocyte
  • Psychiatric disorder
A cellular perspective on brain energy metabolism and imaging
Year: 2015 ISSN:DOI: 10.1016/j.neuron.2015.03.035
Authors: Magistretti P.J., Allaman I.
  • Animals
  • Astrocytes
  • Brain
  • Energy metabolism
  • Glucose
  • Humans
  • Magnetic Resonance Imaging
  • Neurons
Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect
Year: 2015 ISSN:DOI: 10.3389/fphys.2014.00522
Authors: Demetrius L.A., Magistretti P.J., Pellerin L.
  • Age-related disease
  • Inverse cancer comorbidity
  • Metabolic alteration
  • Mitochondrial dysregulation
  • The inverse warburg effect
​Astrocytes: new targets for the treatment of neurodegenerative diseases
Year: 2015 ISSN:DOI: 10.2174/1381612821666150710144502
Authors: Finsterwald C., Magistretti P.J., Lengacher S.
  • Alzheimer disease
  • Amyotrophic Lateral Sclerosis
  • Astrocyte
  • Glia
  • Lactate
  • Metabolism
  • Neurodegeneration
  • Parkinson's disease
Goals in nutrition science 2015-2020
Year: 2015 ISSN:Doi: 10.3389/fnut.2015.00026
Authors: Allison D.B., Bassaganya-Riera J., Burlingame B., Brown A.W., Le Coutre J., Dickson S.L., Van Eden W., Garssen J., Hontecillas R., Khoo C.S., Knorr D., Kussmann M., Magistretti P.J., Mehta T., Meule A., Rychlik M., Vögele C.
  • Nutrition
  • Food
  • Mitigating Errors
  • Big Data Analysis
Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush
Year: 2015 ISSN:DOI: 10.1016/j.expneurol.2014.10.018
Authors: Morrison B.M., Tsingalia A., Vidensky S., Lee Y., Jin L., Farah M.H., Lengacher S., Magistretti P.J., Pellerin L., Rothstein J.D.
  • Axon
  • Dorsal root ganglion
  • Electron microscopy
  • Metabolism
  • Monocarboxylate transporter
  • Nerve crush
  • Perineurial cell
  • Peripheral nerve
  • Regeneration
  • Schwann cell
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King Abdullah bin Abdulaziz Al Saud, 1924 – 2015

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