Research Interests
During her thesis Engy investigated a potential redox-mediated NMDARs regulation induced by lactate. She performed site-directed mutagenesis of the receptor to eliminate its redox sensitivity. Engy used Calcium imaging in HEK-293 cells to probe NMDARs activity and found that lactate regulates NMDARs activity through an alteration of the cellular redox state.
Research Interests Keywords
Brain energetics
Behavioral neuroscience